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In vitro exploration of potential mechanisms of toxicity of the human hepatotoxic drug fenclozic acid

โœ Scribed by Rodrigues, Alison V. M.; Rollison, Helen E.; Martin, Scott; Sarda, Sunil; Schulz-Utermoehl, Timothy; Stahl, Simone; Gustafsson, Frida; Eakins, Julie; Kenna, J. Gerry; Wilson, Ian D.


Book ID
120326588
Publisher
Springer-Verlag
Year
2013
Tongue
English
Weight
485 KB
Volume
87
Category
Article
ISSN
0340-5761

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## Abstract Significant activity has been identified using S9788, a triazineaminopiperidine derivative, as a new modulator of multidrug resistance against a series of drugโ€resistant human tumourโ€cell lines __in vitro__. Maximal nonโ€cytotoxic concentrations (__i.e.__, those resulting in โ‰ค 10% cytoto