𝔖 Bobbio Scriptorium
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In vitro evidence for the participation of intestinal opioids in the control of peristalsis in the guinea pig small intestine

✍ Scribed by W. Kromer; W. Pretzlaff

Book ID
112343718
Publisher
Springer-Verlag
Year
1979
Tongue
English
Weight
464 KB
Volume
309
Category
Article
ISSN
0028-1298

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## Background Inhibition of intestinal peristalsis is a major side effect of opioid analgesics. Although tramadol is an opioid-like analgesic, its effect on gut motility is little known. Therefore, the effect of (+)-tramadol, (-)-tramadol and the major metabolite __O__-desmethyltramadol on intestin