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In vitro evidence for auto-induction of artemisinin metabolism in the rat

✍ Scribed by S. Gupta; U. S. H. Svensson; M. Ashton


Publisher
Springer-Verlag
Year
2001
Tongue
English
Weight
647 KB
Volume
26
Category
Article
ISSN
0378-7966

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✍ W. N. Wu; L. A. McKown; P. J. O'Neill πŸ“‚ Article πŸ“… 1995 πŸ› John Wiley and Sons 🌐 English βš– 541 KB

Fenobam [(Fn); N-(3-chlorophenyl)-N-(4,5-dihydro-l -methyl-4-0x0-1 Kimidazole-2-yl)urea] sulfate is a novel agent with potent anxiolytic activity in rats. [14C]Fn sulfate was administered as an oral solution (250 mglkg) to male Wistar rats, and 52% of the administered dose was excreted in urine (0-5