In vitro evaluation of sustained-release tablets by dual channel scintillation counting

Sustained-release and swelling character

Sustained-release and swelling characteristics of xanthan gum/ethylcellulose-based injection moulded matrix tablets: in vitro and in vivo evaluation

✍ T. Quinten; T. De Beer; F. O. Onofre; G. Mendez-Montealvo; Y. J. Wang; J. P. Rem 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 419 KB

Sustained-release matrix tablets were developed by injection moulding using metoprolol tartrate (MPT) and ethylcellulose (EC) as sustained-release agent. Dibutyl sebacate was selected as plasticiser. The influence of matrix composition, plasticiser concentration, and drug load on drug release was ev