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In vitro evaluation of sustained-release matrix tablets prepared with new modified polymeric carbohydrates

✍ Scribed by M.V. Velasco; A. Muñoz; M.R. Jiménez-Castellanos; I. Castellano; I. Goñi; M. Gurruchaga

Book ID
113368466
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
645 KB
Volume
136
Category
Article
ISSN
0378-5173

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Sustained-release matrix tablets were developed by injection moulding using metoprolol tartrate (MPT) and ethylcellulose (EC) as sustained-release agent. Dibutyl sebacate was selected as plasticiser. The influence of matrix composition, plasticiser concentration, and drug load on drug release was ev