Lipoprotein effects on aβ accumulation a
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Greg M. Cole; Walter Beech; Sally A. Frautschy; Jason Sigel; Connie Glasgow; Mar
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Article
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1999
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John Wiley and Sons
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English
⚖ 537 KB
An inflammatory response involving activated microglia in neuritic -amyloid plaques is found in Alzheimer's disease (AD) brain. Because HDL lipoproteins have been shown to carry the -amyloid peptide (A) in plasma and CSF, we have investigated the influence of plasma high-density lipoprotein (HDL)