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In vitro effects of picotamide on human platelet aggregation, the release reaction and thromboxane B2 production

✍ Scribed by M. Cattaneo; P.M. Tenconi; A. Lecchi; P.M. Mannucci

Book ID
119038249
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
505 KB
Volume
62
Category
Article
ISSN
0049-3848

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β€œIn vitro” and β€œex vivo” effects of picotamide, a combined thromboxane A2-synthase inhibitor and -receptor antagonist, on human platelets
✍ M. Berrettini; M. Cunto; P. Parise; S. Grasselli; G. G. Nenci πŸ“‚ Article πŸ“… 1990 πŸ› Springer 🌐 English βš– 599 KB

Picotamide (G 137), a new non prostanoid inhibitor of in vitro arachidonic acid induced platelet aggregation, has been further characterized in in vitro and ex vivo studies. When whole blood was activated with collagen in the presence of picotamide 5 x 10(-4) M, thromboxane B2 production was decreas