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In vitro effects of folate derivatives on valproate-induced neural tube defects in mouse and rat embryos

โœ Scribed by Hansen, D.K.


Book ID
122582806
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
658 KB
Volume
7
Category
Article
ISSN
0887-2333

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## Abstract Early somite mouse embryos were exposed in vitro to xylocaine (Lignocaine hydrochloride) to examine its effect on neural tube closure. When embryos were exposed to 2.4 ร— 10^โˆ’4^ mg/ml xylocaine for the entire 36โ€hour culture period, cephalic neural tube closure did not take place. When e