In vitro effects of 1,1-dimethylhydrazine on hydrogen peroxide-induced suppression of lymphocyte blast transformation
β Scribed by Don Frazier; Melinda J. Tarr; Richard G. Olsen
- Publisher
- Elsevier Science
- Year
- 1987
- Tongue
- English
- Weight
- 42 KB
- Volume
- 47
- Category
- Article
- ISSN
- 0300-483X
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Ca antagonists of dierent classes (verapamil, nifedipine, nicardipine, diltiazem) in a concentration of 10 Γ5 M and higher are known to suppress Ca 2 transport into the lymphocyte cytosol, changing a normal response of lymphocytes to mitogens and antigens and so inhibiting their proliferation, as we
Both IDDM and NIDDM are characterized by deviations in peripheral T and B lymphocyte count, T helper : T suppressor ratio, as well as by impaired T suppressor function. These abnormalities may promote insulin antibody and other antibody production, contributing to overt diabetes mellitus development
We tested the effect of TGF-PI on the EBV-induced activation and immortalization of human B lymphocytes. In Iymphocyte cultures of EBV-seropositive individuals, T cells can inhibit the EBV-induced transformation of B cells. We found that in the presence of TGF-f3 I the transformation was more effici