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In vitro effects and clinical evaluation of a human chorionic gonadotrophin preparation in acute leukemia

✍ Scribed by Feldman, E J; Seiter, K; Chiao, J W; Halicka, H D; Traganos, F; Fatora, S R; McMichael, J; Baskind, P; Goff, H; Beer, M

Book ID: 110054003
Publisher: Nature Publishing Group
Year: 1998
Tongue: English
Weight: 340 KB
Volume: 12
Category: Article
ISSN: 0887-6924
DOI: 10.1038/sj.leu.2401196

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## Abstract Bone marrow stromal cells constitute a heterogeneous population, and in the present study we investigated intercellular crosstalk __via__ release of soluble mediators between native human AML blasts and fibroblasts/osteoblasts. Coculture of nonleukemic stromal cells and AML blasts separ