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In vitro effect of benzimidazole and 5-nitroimidazole derivatives on the microtubular system of Trichomonas vaginalis

โœ Scribed by Mattana, A.; Franconi, F.; Manca, P.; Juliano, C.; Cappuccinelli, P.


Book ID
122672118
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
117 KB
Volume
22
Category
Article
ISSN
1043-6618

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AdoHcy hydrolase of Trichomonas vaginali
โœ Padraick J. Dornbush; Guillermo Vazquez-Anaya; Ajit Shokar; Saoly Benson; Magdal ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 871 KB

a c t Trypanosoma brucei and Trichomonas vaginalis are both parasitic protozoans that are known to share many similar biochemical pathways. Aristeromycin, as well as 5 0 -iodovinyl and 5 0 -oxime analogues of adenosine, are potent inhibitors of AdoHcy hydrolase in T. brucei, an enzyme that catalyses