AdoHcy hydrolase of Trichomonas vaginali
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Padraick J. Dornbush; Guillermo Vazquez-Anaya; Ajit Shokar; Saoly Benson; Magdal
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Article
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2010
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Elsevier Science
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English
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a c t Trypanosoma brucei and Trichomonas vaginalis are both parasitic protozoans that are known to share many similar biochemical pathways. Aristeromycin, as well as 5 0 -iodovinyl and 5 0 -oxime analogues of adenosine, are potent inhibitors of AdoHcy hydrolase in T. brucei, an enzyme that catalyses