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In vitro effect of anti-calla and anti-ba1 monoclonal antibodies on clonogenic leukemic cells in acute lymphoblastic leukemia

✍ Scribed by J.P. Marie; C. Choquet; J.Y. Perrot; D. Thevenin; R. Zittoun


Book ID
113238672
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
90 KB
Volume
10
Category
Article
ISSN
0145-2126

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## Abstract CD19 is an attractive therapeutic target for treating human B‐cell tumors. In our study, chimeric (c) divalent (cHD37) and tetravalent (cHD37‐DcVV) anti‐CD19 monoclonal antibodies (MAbs) were constructed, expressed and evaluated for their binding to human 19‐positive (CD19^+^) tumor cel