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In Vitro Drug Testing of Ovarian Cancer Using the Human Tumor Colony-Forming Assay: Comparison of in Vitro Response and Clinical Outcome

โœ Scribed by Massimo Federico; David S. Alberts; Dava J. Garcia; Julia Emerson; Paul Fanta; Rosa Liu; Sydney E. Salmon


Book ID
115616373
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
431 KB
Volume
55
Category
Article
ISSN
0090-8258

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The fluorometric microculture cytotoxicity assay (FMCA), a short-term in vitro assay based on the concept of total tumor cell kill, was used for testing the cytotoxic drug sensitivity of tumor cells from patients with ovarian carcinoma. A total of 125 fresh specimens was obtained, 98 (78%) of which