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In vitro Drug Sensitivity-Gene Expression Correlations Involve a Tissue of Origin Dependency.

✍ Scribed by C. R. Andersson; M. Fryknaes; L. Rickardson; R. Larsson; A. Isaksson; M. G. Gustafsson


Book ID
102002599
Publisher
John Wiley and Sons
Year
2007
Weight
11 KB
Volume
38
Category
Article
ISSN
0931-7597

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Cell lines derived from three histologically different murine colon tumours (MAC) were used to assess whether or not a tumour colony-forming assay could have retrospectively predicted the wide range of in vivo responses to the alkylating agent, ThioTEPA. Tumour responses ranged from sensitive (MAC 2