## Abstract The prostatic epithelium is functionally organized in stem cell units. This unit consists of a slow turn over stem cell within the basal epithelial layer which can replenish itself and provide progeny which differentiate down either a neuroendocrine or exocrine pathway. The maturation a
In vitro deregulation of markers characteristic of human prostate epithelial cells
β Scribed by Tarin A Islam; Anup Patel; Amir V Kaisary; Angeles Mondragon; Jonathan Waxman; Tahereh Kamalati
- Book ID
- 116915076
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 390 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0040-8166
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BACKGROUND. An in vitro model of prostatic stromal cells suitable for experimental studies of the pathogenesis of BPH is still lacking. We therefore standardized the isolation, cultivation, and characterization of human prostatic stromal cell lineages. METHODS. Stromal cells were isolated from a sur
## Abstract Prostate derived factor (PDF) is a member of transforming growth factorβΞ² (TGFβΞ²) superfamily proteins involved in differentiation of the prostate epithelium. Proprotein convertases (PCs) such as furin are thought to mediate the processing of TGFβΞ² superfamily. In the present study, we