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In vitro cytotoxicity of 1,4-naphthoquinone derivatives to replicating cells

✍ Scribed by Babich, H.; Stern, A.; Munday, R.

Book ID
121925369
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
456 KB
Volume
69
Category
Article
ISSN
0378-4274

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In Vitro Cytotoxicities of 1,4-Naphthoqu
In Vitro Cytotoxicities of 1,4-Naphthoquinone and Hydroxylated 1,4-Naphthoquinones to Replicating Cells
✍ H. Babich; A. Stern πŸ“‚ Article πŸ“… 1993 πŸ› John Wiley and Sons 🌐 English βš– 516 KB

Using the human hepatoma cell line, HepG2, and the BALB/c mouse fibroblast cell line, 3T3, as the bioindicators in the neutral red cytotoxicity assay, the effect of hydroxyl substitution on the toxicity of 1,4naphthoquinone was studied. The sequence of potency for the quinones was 5,8-dihydroxy-1,4-