𝔖 Bobbio Scriptorium
✦   LIBER   ✦

In vitro cytotoxicity and genotoxicity testing using upcyte® hepatocytes

✍ Scribed by Nörenberg, Astrid; Sonntag-Buck, Vera; Hewitt, Nicola; Heinz, Stefan; Braspenning, Joris

Book ID
122021764
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
79 KB
Volume
221
Category
Article
ISSN
0378-4274

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Appropriate levels of cytotoxicity for g
Appropriate levels of cytotoxicity for genotoxicity tests using mammalian cells in vitro
✍ Lutz Müller; Toshio Sofuni 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 37 KB

Among standard battery genotoxicity assays, the in vitro chromosome aberration test and the mouse lymphoma tk assay (MLA) yield about fourfold higher incidences of positive test results than the bacterial reverse mutation test or in vivo bone marrow tests. This is a result of experience with submiss