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In vitro cytotoxicity and drug release properties of pH- and temperature-sensitive core–shell hydrogel microspheres

✍ Scribed by Liwei Ma; Mingzhu Liu; Hongliang Liu; Jun Chen; Dapeng Cui

Book ID
108147040
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
646 KB
Volume
385
Category
Article
ISSN
0378-5173

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In vitro cytotoxicity and drug release p
In vitro cytotoxicity and drug release properties of pH- and temperature-sensitive core–shell hydrogel microspheres
✍ Liwei Ma; Mingzhu Liu; Hongliang Liu; Jun Chen; Dapeng Cui 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 646 KB

A simple method has been developed to prepare smart P(N,N-diethylacrylamide-co-methacrylic acid) (P(DEA-co-MAA)) microspheres that consist of well-defined temperature-sensitive cores and pH sensitive shells. The microgels have been prepared by surfactant-free emulsion polymerization using water as t