In vitro cytokine release profile: Predictive value for metastatic potential in head and neck squamous cell carcinomas
β Scribed by Shkeir, Omar; Athanassiou-Papaefthymiou, Maria; Lapadatescu, Martian; Papagerakis, Petros; Czerwinski, Michael J.; Bradford, Carol R.; Carey, Thomas E.; Prince, Mark E. P.; Wolf, Gregory T.; Papagerakis, Silvana
- Book ID
- 118262781
- Publisher
- John Wiley and Sons
- Year
- 2013
- Tongue
- English
- Weight
- 503 KB
- Volume
- 35
- Category
- Article
- ISSN
- 1043-3074
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Background. Prognosis of head and neck squamous cell carcinoma (HNSCC) is strongly associated with cervical lymph node metastasis. Cathepsin-D is a lysosomal protease expressed in all cells. Its role in extracellular matrix degradation is postulated to promote tumor invasion and metastasis. Increase
## Abstract ## Background. Hypoxia and tumor cell proliferation are important factors determining the treatment response of squamous cell carcinomas of the head and neck. Successful approaches have been developed to counteract these resistance mechanisms although usually at the cost of increased s