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In Vitro Cyclooxygenase-2 Protein Expression and Enzymatic Activity in Neoplastic Cells

✍ Scribed by David A. Heller; Timothy M. Fan; Louis-Philippe de Lorimier; Sarah C. Charney; Anne M. Barger; Sarah H. Tannehill-Gregg; Thomas J. Rosol; Matthew A. Wallig

Book ID
118094759
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
399 KB
Volume
21
Category
Article
ISSN
0891-6640

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Background and Objectives: Epidemiological studies have suggested that the regular use of nonsteroidal antiinflammatory drugs, which inhibit cyclooxygenase (COX), reduces the risk of colon cancer. The inducible COX-2 isoform has been reported to be upregulated in colorectal carcinomas and may play a