In vitro catabolic effect of protoporphyrin IX in human osteoblast-like cells: possible role of the 18 kDa mitochondrial translocator protein

Downregulation of the 18-kDa translocato

Downregulation of the 18-kDa translocator protein: Effects on the ammonia-induced mitochondrial permeability transition and cell swelling in cultured astrocytes

✍ K. S. Panickar; A. R. Jayakumar; K. V. Rama Rao; M. D. Norenberg 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 276 KB

## Abstract Hepatic encephalopathy (HE) is a major neurological complication in patients with severe liver disease. While the pathogenesis of HE is unclear, elevated blood and brain ammonia levels are believed to be major etiological factors, and astrocytes appear to be the primary target of its to