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In vitro biodistribution of silver nanoparticles in isolated perfused porcine skin flaps

โœ Scribed by Teresa L. Leavens; Nancy A. Monteiro-Riviere; Alfred O. Inman; James D. Brooks; Steven J. Oldenburg; Jim E. Riviere


Book ID
112117784
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
448 KB
Volume
32
Category
Article
ISSN
0260-437X

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The use of the isolated perfused porcine skin flap (IPPSF), an alternative in vitro animal model, to predict the profile of the concentration of arbutamine in plasma samples from humans after transdermal iontophoretic administration of this novel catecholamine is described. The strategy involved adm