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In vitro binding of a novel dopamine D3 receptor ligand: [125I]trans-7-OH-PIPAT-A

✍ Scribed by Mei-Ping Kung; Hank F. Kung; Sumalee Chumpradit; Catherine Foulon

Book ID: 115888915
Publisher: Elsevier Science
Year: 1993
Tongue: English
Weight: 179 KB
Volume: 235
Category: Article
ISSN: 0014-2999
DOI: 10.1016/0014-2999(93)90839-a

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## Abstract A new dopamine D2‐like receptor ligand, (__R,S__)__trans__‐5‐hydroxy‐2‐[N‐n‐propyl‐N‐(3′‐iodo‐2′‐propenyl)amino]tetralin ((__R,S)trans__‐5‐OH‐PIPAT, 3), based on high affinity dopamine receptor agonist 5‐hydroxy‐2‐[N,N‐(di‐n‐propyl)‐2‐amino]tetralin (5‐OH‐DPAT, 1). was prepared. The syn