In vitro autoradiography of ionotropic glutamate receptors in hippocampus and striatum of aged Long–Evans rats: relationship to spatial learning

Visualization of muscarinic receptor-med

Visualization of muscarinic receptor-mediated phosphoinositide turnover in the hippocampus of young and aged, learning-impaired Long Evans rats

✍ Michelle M. Nicolle; Michela Gallagher; Michael McKinney 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 570 KB

## Abstract Hippocampal receptor‐mediated phosphoinositide (PI) turnover is severely blunted in aged rats that demonstrate cognitive deficits in the Morris water maze. To further examine the anatomical localization of this deficit, we examined the topography of muscarinic receptor‐mediated PI turno