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In vitro antiviral effects of an aqueous extract of Artemisia verlotorum Lamotte (Asteraceae)

✍ Scribed by Vincenzo Calderone; Elisa Nicoletti; Patrizia Bandecchi; Mauro Pistello; Paola Mazzetti; Enrica Martinotti; Ivano Morelli

Publisher: John Wiley and Sons
Year: 1998
Tongue: English
Weight: 91 KB
Volume: 12
Category: Article
ISSN: 0951-418X
DOI: 10.1002/(sici)1099-1573(199812)12:8<595::aid-ptr352>3.0.co;2-6

No coin nor oath required. For personal study only.

✦ Synopsis

Plants represent a possible source of new interesting antiviral drugs. An aqueous extract of Artemisia verlotorum exhibited, in vitro, strong activity against the feline immunodeficiency virus (FIV), which can be considered a reliable model of the human immunodeficiency virus type 1, the aetiological agent of AIDS. The extract determined a decrease of the virus-induced syncytia in the cultured cells, an inhibition of the viral reverse transcriptase activity and a reduction of the viral capsid protein P24 expression.

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