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In vitro antigenic reactivity of synthetic lipid a analogues as determined by monoclonal and conventional antibodies

✍ Scribed by Nobuhiko Kasai; Satoru Arata; Jun-ichi Mashimo; Kenji Okuda; Yukoh Aihara; Shozo Kotani; Haruhiko Takada; Tetsuo Shiba; Shoichi Kusumoto


Book ID
115758184
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
331 KB
Volume
128
Category
Article
ISSN
0006-291X

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## Abstract Two monoclonal antibodies (KH‐1 and KH‐2) against a transplanted fibrosarcoma (KMT‐17) in WKA rats were produced by fusing a mouse myeloma (P~3~‐X63‐Ag8.653) with spleen cells from syngeneic rats hyperimmunized with KMT‐17. Both antibodies showed complement‐dependent cytotoxicity agains