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In vitro and in vivo testing techniques for allergic contact dermatitis*1

โœ Scribed by GERBERICK, G

Book ID
123359106
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
895 KB
Volume
9
Category
Article
ISSN
1532-8163

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Sensitizing capacity of three methyl alk
Sensitizing capacity of three methyl alkanesulphonates: a murine in vivo and in vitro model of allergic contact dermatitis
โœ R. Fraginals; J. -P. Lepoittevin; C. Benezra ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› Springer-Verlag ๐ŸŒ English โš– 397 KB

A murine model for in vivo and in vitro studies of contact sensitization to methyl alkanesulphonate derivatives has been developed. Contact sensitivity was quantified in vivo by measuring the ear thickness increase, and the influence of the alkyl chain length (hexyl, dodecyl, hexadecyl) was investig