Bispecific antibody targeting of doxorub
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C.H.J. Ford; P.A. Osborne; B.G. Rego; A. Mathew
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Article
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2001
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John Wiley and Sons
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French
⚖ 120 KB
A bispecific monoclonal antibody (BsMAb) recognising carcinoembryonic antigen (CEA) and doxorubicin (Dox) was used in colorimetric microcytotoxicity assays with 3 human colon cancer cell lines (COLO320DM, SKCO1 and LS174T) showing no, high or medium CEA expression, respectively. The IC50 values for