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In vitro and in vivo studies demonstrating potent and selective estrogen inhibition with the nonsteroidal aromatase inhibitor CGS 16949A

โœ Scribed by Ronald E. Steele; Lynn B. Mellor; Wilbur K. Sawyer; Jong M. Wasvary; Leslie J. Browne

Book ID
116065052
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
878 KB
Volume
50
Category
Article
ISSN
0039-128X

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## Background: Fadrozole hydrochloride (cgs 16949a) is a highly potent, nonsteroidal aromatase inhibitor that significantly lowers estrogen levels in postmenopausal women and can be effective therapy for patients with advanced hormone-dependent breast carcinoma. circulating estradiol, estrone, and