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In vitro and in vivo protection against kainate-induced excitotoxicity by melatonin

✍ Scribed by Pietro Giusti; Davide Franceschini; Marcella Petrone; Hari Manev; Maura Floreani

Book ID
111263933
Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
598 KB
Volume
20
Category
Article
ISSN
0742-3098

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✍ Henrich Cheng; Yu-Show Fu; Jiun-Wen Guo πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 556 KB

## Abstract The primary aim of this study is to explore the protective mechanisms of glial‐derived neurotrophic factor (GDNF) during excitotoxicity by kainate in the hippocampus. After a 15‐min microinjection with kainate, excitotoxicity was induced in the rat hippocampus. The protective effect of