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In Vitro and In Vivo Photosensitization by Protoporphyrins Possessing Different Lipophilicities and Vertical Localization in the Membrane

✍ Scribed by Irena Bronshtein; Svetlana Aulova; Asta Juzeniene; Vladimir Lanl; Li-Wei Ma; Kevin M. Smith; Zvi Malik; Johan Moan; Benjamin Ehrenberg


Book ID
111837382
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
803 KB
Volume
82
Category
Article
ISSN
0031-8655

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The spectroscopic and biological properties of the new photosensitizer lutetium texaphyrin (Lu-Tex) were assessed in vitro and in vivo on a C26 colon carcinoma model, in comparison with hematoporphyrin (Hp), photofrin II (PII) and chlorin e 6 (Chl). Strong binding of Lu-Tex to lipid bilayer membrane