✦ LIBER ✦

In vitro and in vivo pharmacological profile of 4-(4-fluorobenzylidene)-1-{2-[5-(4-fluorophenyl)-1H-pyrazol-4-yl] ethyl} piperidine (NRA0161)

✍ Scribed by Yoshiko Suzuki; Takeo Funakoshi; Shigeyuki Chaki; Naoya Kawashima; Shin-ichi Ogawa; Toshihito Kumagai; Atsurou Nakazato; Toshi Komurasaki; Shigeru Okuyama

Book ID: 117173752
Publisher: Elsevier Science
Year: 2002
Tongue: English
Weight: 193 KB
Volume: 71
Category: Article
ISSN: 0024-3205
DOI: 10.1016/s0024-3205(02)02085-4

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

In vitro and in vivo pharmacological pro

In vitro and in vivo pharmacological profile of 5-{2-[4-(6-fluoro-1H-indole-3-yl)piperidin-1-yl]ethyl}-4-(4-fluorophenyl)thiazole-2-carboxylic acid amide (NRA0562), a novel and putative atypical antipsychotic

✍ Takeo Funakoshi; Shigeyuki Chaki; Naoya Kawashima; Yoshiko Suzuki; Ryoko Yoshika 📂 Article 📅 2002 🏛 Elsevier Science 🌐 English ⚖ 261 KB

Antipsychotic profile of 5-{2-[4-(6-fluo

Antipsychotic profile of 5-{2-[4-(6-fluoro-1H-indole-3-yl)piperidin-1-yl]ethyl}-4-(4-fluorophenyl)thiazole-2-carboxylic acid amide (NRA0562) in rats

✍ Kazuaki Takamori; Takeo Funakoshi; Shiho Hirota; Shigeyuki Chaki; Kazuya Kameo 📂 Article 📅 2002 🏛 Elsevier Science 🌐 English ⚖ 137 KB

In vitro and in vivo pharmacological cha

In vitro and in vivo pharmacological characterisation of the potent and selective vasopressin V1A receptor antagonist 4-[4-(4-Chloro-phenyl)-5-[1,2,3]triazol-2-ylmethyl-4H-[1,2,4]triazol-3-yl]-piperidin-1-yl-(3,5-difluoro-phenyl) methanone (PF-00738245)

✍ Rachel Russell; Rachel Doyle; Jamie Turner; Neil Attkins; Simeon Ramsey; Laura W 📂 Article 📅 2011 🏛 Elsevier Science 🌐 English ⚖ 786 KB

Design, synthesis, and preliminary in vi

Design, synthesis, and preliminary in vitro and in vivo pharmacological evaluation of 4-{4-[2-(4-(2-substitutedquinoxalin-3-yl)piperazin-1-yl)ethyl]phenyl}thiazoles as atypical antipsychotic agents

✍ Kondapalli Venkata Gowri Chandra Sekhar… 📂 Article 📅 2012 🏛 Springer-Verlag 🌐 English ⚖ 397 KB

In vivo evaluation of [123I]-4-(2-(bis(4

In vivo evaluation of [123I]-4-(2-(bis(4-fluorophenyl)methoxy)ethyl)-1-(4-iodobenzyl)piperidine, an iodinated SPECT tracer for imaging the P-gp transporter

✍ Sylvie De Bruyne; Leonie Wyffels; Terrence L. Boos; Steven Staelens; Steven Dele 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 746 KB

Synthesis, radiosynthesis and preliminar

Synthesis, radiosynthesis and preliminary in vivo evaluation of [123I]-(4-fluorophenyl) {1-[2-(2-iodophenyl)ethyl]piperidin-4-yl}methanone, a potential 5-HT2A-antagonist for SPECT brain imaging

✍ P. Blanckaert; M. Vandecapelle; L. Staelens; I. Burvenich; R. A. Dierckx; G. Sle 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 French ⚖ 106 KB 👁 1 views

## Abstract Many people suffer from psychiatric illnesses like depression and anorexia. Relevant to these diseases is amongst others a malfunctioning of brain 5‐HT~2A~‐receptors. To allow __in vivo__ quantification of these receptors with Single Photon Emission Computerized Tomography (SPECT), a ra