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In vitro and in vivo neuroprotective effect and mechanisms of glabridin, a major active isoflavan from Glycyrrhiza glabra (licorice)

✍ Scribed by Xue-Qing Yu; Charlie Changli Xue; Zhi-Wei Zhou; Chun-Guang Li; Yao-Min Du; Jun Liang; Shu-Feng Zhou


Book ID
116719275
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
926 KB
Volume
82
Category
Article
ISSN
0024-3205

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## Abstract Amyotrophic lateral sclerosis (ALS) is the most common fatal motor neuron disease, affecting mostly middle‐aged people. There are no curative therapies for ALS. Several lines of evidence have supported the notion that the proapoptotic property of familial ALS (FALS)‐linked mutant Cu/Zn‐