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In vitro and in vivo localization of prostaglandin H synthase in fetal sheep neurons

✍ Scribed by Clara R Thore; Tracy C Beasley; David W Busija

Book ID
117476467
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
904 KB
Volume
242
Category
Article
ISSN
0304-3940

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## ABSTUCT We have used immunofluorescent techniques to examine the distribution of prostaglandin H synthase (PGHS) in ovine astrocyte-enriched secondary cultures and in mixed cortical cells in primary culture. A batteq of monoclonal and polyclonal antibodies specific for the constitutive (PGHS-1)

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The growth factor-and phorbol ester-inducible prostaglandin H synthase (PGHS)-2 has been found to be constitutively overexpressed in epidermal tumors generated by the initiation-promotion protocol in murine skin, whereas the expression of PGHS-1 does not change under these conditions. In this paper