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In Vitro and In Vivo gene delivery mediated by Lactosylated Dendrimer/α-Cyclodextrin Conjugates (G2) into Hepatocytes

✍ Scribed by Hidetoshi Arima; Shogo Yamashita; Yoshimasa Mori; Yuya Hayashi; Keiichi Motoyama; Kenjiro Hattori; Tomoko Takeuchi; Hirofumi Jono; Yukio Ando; Fumitoshi Hirayama; Kaneto Uekama


Book ID
113693363
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
764 KB
Volume
146
Category
Article
ISSN
0168-3659

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✍ Loïc Vincent; Julia Varet; Jean-Yves Pille; Heidi Bompais; Paule Opolon; Andrei 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 French ⚖ 785 KB

## Abstract Gene transfer is an attractive approach to fight cancer by targeting cancer cells or their vasculature. Our study reports the inhibition of tumor growth and angiogenesis by a nonviral method using dendrimers associated with 36‐mer anionic oligomers (ON36) for delivering angiostatin (Kri