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In vitro and in vivo expressions of transforming growth factor-α and tyrosine kinase receptors in human non-small-cell lung carcinomas


Book ID
122919048
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
145 KB
Volume
11
Category
Article
ISSN
0169-5002

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The effect of tyrosine kinase inhibitor, erbstatin, on cell growth and mRNA expression of growth-factor/receptor system was examined in 6 human gastric-carcinoma cell lines. Erbstatin inhibited both EGF-induced and serum-stimulated cell growth of all 6 cell lines (TMK-I, MKN-I, -7, -28, -45, -74) in