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In Vitro and In Vivo Evidence for Anti-Inflammatory Properties of 2-Methoxyestradiol

✍ Scribed by Shand, F. H. W.; Langenbach, S. Y.; Keenan, C. R.; Ma, S. P.; Wheaton, B. J.; Schuliga, M. J.; Ziogas, J.; Stewart, A. G.

Book ID
125495945
Publisher
American Society for Pharmacology and Experimental Therapeutics
Year
2010
Tongue
English
Weight
799 KB
Volume
336
Category
Article
ISSN
0022-3565

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In vitro and in vivo antitumor effect of
In vitro and in vivo antitumor effect of 2-methoxyestradiol on human melanoma
✍ Judit Dobos; József Tímár; József Bocsi; Zsuzsanna Burián; Katalin Nagy; Gábor B 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 French ⚖ 462 KB 👁 1 views

## Abstract 2‐methoxyestradiol (2ME~2~) is an endogenous metabolite of estradiol with estrogen‐receptor‐independent antitumor and antiangiogenic activity. We examined the effects of 2ME~2~ on the cellular proliferation of 8 human melanoma cell lines. We show that 2ME~2~ inhibited cell proliferation