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In vitro and in vivo effects of the carbon monoxide-releasing molecule, CORM-3, in the xenogeneic pig-to-primate context

✍ Scribed by Marta Vadori; Michela Seveso; Federica Besenzon; Erika Bosio; Elena Tognato; Fabio Fante; Massimo Boldrin; Sabrina Gavasso; Licia Ravarotto; Brian E. Mann; Paolo Simioni; Ermanno Ancona; Roberto Motterlini; Emanuele Cozzi

Book ID
110905039
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
588 KB
Volume
16
Category
Article
ISSN
0908-665X

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The carbon monoxide-releasing molecule,
The carbon monoxide-releasing molecule, corm-3 (ru(co)3cl(glycinate)), targets respiration and oxidases in campylobacter jejuni, generating hydrogen peroxide
✍ Holly Smith; Brian E. Mann; Roberto Motterlini; Robert K. Poole 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 556 KB

## Abstract Carbon monoxide (CO) is a classical respiratory inhibitor, but CO‐releasing molecules (CO‐RMs) have therapeutic value, increasing phagocytosis, and reducing sepsis‐induced lethality. CORM‐3, Ru(CO)~3~Cl(glycinate), a ruthenium‐based carbonyl that liberates CO under physiological conditi