✦ LIBER ✦

IN VITRO AND IN VIVO DRUG INTERACTIONS INVOLVING HUMAN CYP3A

✍ Scribed by Thummel, K. E.; Wilkinson, G. R.

Book ID: 115512484
Publisher: Annual Reviews
Year: 1998
Tongue: English
Weight: 298 KB
Volume: 38
Category: Article
ISSN: 0362-1642
DOI: 10.1146/annurev.pharmtox.38.1.389

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

In vitro-in vivo extrapolation of zolpid

In vitro-in vivo extrapolation of zolpidem as a perpetrator of metabolic interactions involving CYP3A

✍ Thomas M. Polasek; Janani S. Sadagopal; David J. Elliot; John O. Miners 📂 Article 📅 2009 🏛 Springer 🌐 English ⚖ 211 KB

In vitro -to- in vivo predictions of dru

In vitro -to- in vivo predictions of drug–drug interactions involving multiple reversible inhibitors

✍ Lutz, Justin D; Isoherranen, Nina 📂 Article 📅 2012 🏛 Informa plc 🌐 English ⚖ 624 KB

In Vitro/in Vivo scaling of alprazolam m

In Vitro/in Vivo scaling of alprazolam metabolism by CYP3A4 and CYP3A5 in humans

✍ Noriko Hirota; Kiyomi Ito; Takafumi Iwatsubo; Carol E. Green; Charles A. Tyson; 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 243 KB 👁 1 views

We attempted to predict the in vivo metabolic clearance of alprazolam from in vitro metabolic studies using human liver microsomes and human CYP recombinants. Good correlations were observed between the intrinsic clearance (CL int ) for 4-hydroxylation and CYP3A4 content and between the CL int for a

Herb-Drug Interaction of 50 Chinese Herb

Herb-Drug Interaction of 50 Chinese Herbal Medicines on CYP3A4 Activity in Vitro and in Vivo

✍ Pao, Li-Heng; Hu, Oliver Yoa-Pu; Fan, Hsien-Yuan; Lin, Chang-Ching; Liu, Liang-C 📂 Article 📅 2012 🏛 World Scientific Publishing Company 🌐 English ⚖ 252 KB

Fluoxetine- and Norfluoxetine-Mediated C

Fluoxetine- and Norfluoxetine-Mediated Complex Drug–Drug Interactions: In Vitro to In Vivo Correlation of Effects on CYP2D6, CYP2C19, and CYP3A4

✍ Sager, J E; Lutz, J D; Foti, R S; Davis, C; Kunze, K L; Isoherranen, N 📂 Article 📅 2014 🏛 Nature Publishing Group 🌐 English ⚖ 324 KB

PXR/CYP3A4-Humanized Mice for Studying D

PXR/CYP3A4-Humanized Mice for Studying Drug–Drug Interactions Involving Intestinal P-Glycoprotein

✍ Holmstock, Nico; Gonzalez, Frank J.; Baes, Myriam; Annaert, Pieter; Augustijns, 📂 Article 📅 2013 🏛 American Chemical Society 🌐 English ⚖ 669 KB