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In vitro and in vivo dose-dependent inhibition of methylmercury on glutamine synthetase in the brain of different species

✍ Scribed by Oh-Seung Kwon; Young-Jin Park


Book ID
117766181
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
373 KB
Volume
14
Category
Article
ISSN
1382-6689

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The activities of six aminoacyl-tRNA synthetase species were determined using enzyme preparations partially purified from the brains of control and methylmercury (MeHg)-treated rats. The activities of Asp-, Leu- and Tyr-tRNA synthetases were significantly reduced in the brains of MeHg-intoxicated ra