𝔖 Bobbio Scriptorium
✦   LIBER   ✦

In vitro and in vivo characterization of SGI-1252, a small molecule inhibitor of JAK2

✍ Scribed by Kausar Begam Riaz Ahmed; Steven L. Warner; Andrew Chen; Eric S. Gourley; Xiaohui Liu; Hariprasad Vankayalapati; Roberto Nussenzveig; Josef T. Prchal; David J. Bearss; Charles J. Parker

Book ID
113616705
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
965 KB
Volume
39
Category
Article
ISSN
0301-472X

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

In vitro and in vivo prevention of HIV p
In vitro and in vivo prevention of HIV protease inhibitor-induced insulin resistance by a novel small molecule insulin receptor activator
✍ Mingshan Cheng; Seiyu Chen; Steven R. Schow; Vara Prasad Manchem; Wayne R. Speva 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 264 KB

## Abstract Protease inhibitor (PI) therapy for the treatment of patients infected with human immunodeficiency virus is frequently associated with insulin resistance and diabetic complications. These adverse effects of PI treatment result to a large extent from their inhibition of insulin‐stimulate

Effects of small molecule inhibitors of
Effects of small molecule inhibitors of PI3K/Akt/mTOR signaling on neuroblastoma growth in vitro and in vivo
✍ Lova Segerström; Ninib Baryawno; Baldur Sveinbjörnsson; Malin Wickström; Lotta E 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 French ⚖ 691 KB

## Abstract Activation of the PI3K/Akt signaling pathway is correlated with poor prognosis in neuroblastoma, the most common and deadly extracranial tumor of childhood. In this study, we show that the small‐molecule inhibitors of phosphoinositide‐dependent protein kinase‐1 (PDK1) OSU03012 and the d