𝔖 Bobbio Scriptorium
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In vitro and in vivo binding studies with a monoclonal antibody directed against the PLC/PRF/5 cell line

Book ID
122653982
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
56 KB
Volume
1
Category
Article
ISSN
0168-8278

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## Abstract CD19 is an attractive therapeutic target for treating human B‐cell tumors. In our study, chimeric (c) divalent (cHD37) and tetravalent (cHD37‐DcVV) anti‐CD19 monoclonal antibodies (MAbs) were constructed, expressed and evaluated for their binding to human 19‐positive (CD19^+^) tumor cel