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In Vitro and In Vivo Aldose Reductase Inhibitory Activity of Standardized Extracts and the Major Constituent of Andrographis paniculata

โœ Scribed by Ciddi Veeresham; Ettireddy Swetha; Ajmeera Rama Rao; Kaleab Asres


Book ID
112183770
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
99 KB
Volume
27
Category
Article
ISSN
0951-418X

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In vitro aldose reductase inhibitory act
โœ Jack Deruiter; Abram N. Brubaker; Martha A. Garner; Jeffrey M. Barksdale; Charle ๐Ÿ“‚ Article ๐Ÿ“… 1987 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 427 KB

A number of N-benzenesulfonylglycines, alanines, sarcosine, and prolines, which contain the minimum pharmacophore moieties necessary for aldose reductase inhibitory activity, were prepared and tested in the rat lens assay. In this assay, the benzenesulfonylglycines are considerably more potent than