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In vitro and in vivo activated T cells display increased sensitivity to PGE2

✍ Scribed by Raute Sunder-Plaβmann; Otto Majdic; Walter Knapp; Wolfgang Holter


Book ID
113134768
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
780 KB
Volume
138
Category
Article
ISSN
0008-8749

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We transduced a human gastric carcinoma cell line, HR, with the interleukin 2 (IL-2) gene. Stable HR transfectants secreted nanogram quantities of biologically active IL-2 and had significantly increased expression of IL-2 mRNA relative to that in parental cells. Expression of intracellular IL-2 pro