Evaluation of the mass balance assumptio
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K. Dackson; J. A. Stone; K. J. Palin; W. N. Charman
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Article
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1992
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John Wiley and Sons
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English
β 534 KB
Methods of analyzing drug absorption data from rat intestinal-perfusion experiments are discussed in terms of mass-transfer resistances, or reciprocal permeabilities, and mass balances. Typically, a two-resistance model is used to determine the dimensionless effective permeability (P\*eff) by measur