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In vitro and ex vivo effects of indobufen on red blood cell deformability

✍ Scribed by S. Grasselli; R. Guerciolini; V. Iadevaia; P. Parise; P. Gresele; G. G. Nenci

Publisher
Springer
Year
1987
Tongue
English
Weight
352 KB
Volume
32
Category
Article
ISSN
0031-6970

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## Abstract Hydroxyurea is a drug that is used to treat some patients with sickle cell disease. We have measured the deformability of sickle erythrocytes incubated in hydroxyurea in vitro and found that hydroxyurea acts to decrease the deformability of these cells. The deformability of normal eryth