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In Vitro Analysis of the Effect of Microtubule Acetylation on Kinesin Motility

✍ Scribed by Kaul, Neha; Verhey, Kristen J.; Meyhöfer, Edgar

Book ID
123042169
Publisher
Biophysical Society
Year
2010
Tongue
English
Weight
60 KB
Volume
98
Category
Article
ISSN
0006-3495

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Lipopolysaccharide (LPS) is a main trigger substance for the development of septic shock and multiple organ failure. We showed by turbidity measurements that LPS inhibits microtubule formation in a pH‐dependent manner. Inhibition was found to be not only due to sequestration of MAP2 by LPS, but also