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In vitro analysis of population specific splicing variants of BRCA1 gene

✍ Scribed by J. Sevcik; E. Vondruskova; P. Pohlreich; F. Lhota; E. Matouskova; E. Bursikova; Z. Kleibl


Book ID
119598905
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
89 KB
Volume
6
Category
Article
ISSN
1359-6349

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## Abstract Mutations in __BRCA1__ and __BRCA2__ genes confer a high risk of breast and ovarian cancer. As such, their identification is essential to reduce the risk of disease in healthy carriers, as well as in carriers who have already developed the disease because they are at increased risk for