𝔖 Bobbio Scriptorium
✦   LIBER   ✦

In vitro analysis of gene depression in goldfish choroidal melanophores

✍ Scribed by Kajishima, Takao


Publisher
John Wiley and Sons
Year
1975
Tongue
English
Weight
538 KB
Volume
191
Category
Article
ISSN
0022-104X

No coin nor oath required. For personal study only.

✦ Synopsis


Abstract

The common goldfish depigments its larval choroidal melanophores as well as the skin melanophores for about two to three months following hatching. Thereafter it begins to show a characteristic xanthic coloration. This depigmentation is under the control of depigmentation genes Dp~1~ and Dp~2~. The larval choroidal melanophores of the common goldfish were cultured in vitro for more than four months without showing any sign of depigmentation. During the same period the skin and choroidal melanophores in the control fish had completely depigmented. The addition of thyroid hormone and ACTH to the culture medium had no effect on depigmentation. The mechanisms of depigmentation in the goldfish are discussed.


πŸ“œ SIMILAR VOLUMES


In vitro response of goldfish (Carassius
✍ Joel Abramowitz; Walter Chavin πŸ“‚ Article πŸ“… 1974 πŸ› John Wiley and Sons 🌐 English βš– 724 KB

## Abstract cAMP, dbcAMP, cCMP, cGMP, theophylline and caffeine caused reversible melanosome dispersion within 5 minutes at 10 mM in the dermal melanophores of the black goldfish, __Carassius auratus__ L. cTMP, cUMP, 5′‐AMP, 5′‐CMP, 5′‐GMP, 5′‐TMP, and 5′‐UMP did not produce melanosome dispersion o

Control and Statistical Analysis of in V
✍ Nick J. Plant; Malcolm Ogg; Martin Crowder; G.Gordon Gibson πŸ“‚ Article πŸ“… 2000 πŸ› Elsevier Science 🌐 English βš– 106 KB

The use of in vitro gene reporter assays is becoming increasingly widespread in biology and particularly in drug metabolism, where the need for rapid screening of novel compounds is a driving factor. There is, however, little standardization of technique in the control of such assays, nor in the int

In vitro gene expression analysis of hep
✍ Hiromi Suzuki; Tomoaki Inoue; Tomochika Matsushita; Kazuko Kobayashi; Ikuo Horii πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 112 KB πŸ‘ 1 views

## Abstract The study examined the feasibility of screening for hepatotoxicity by an __in vitro__ gene expression analysis using rat primary hepatocytes and Affymetrix Rat Toxicology U34 arrays. Hepatocytes were exposed for 6 or 24 h to eight drugs, with different mechanisms of hepatotoxicity, at o

Metabolic depression in land snails: In
✍ Brooks, Stephen P. J. ;Storey, Kenneth B. πŸ“‚ Article πŸ“… 1994 πŸ› John Wiley and Sons 🌐 English βš– 767 KB

## Abstract Isolated tissues from the land snail __Otala lactea__ were used to examine the relationship between protein kinase activity and phosphorylation‐induced changes associated with metabolic depression. Hepatopancreas and foot muscle were removed from active and estivating land snails and in

In vitro gene expression analysis of nep
✍ Hiromi Suzuki; Tomoaki Inoue; Tomochika Matsushita; Kazuko Kobayashi; Ikuo Horii πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 142 KB πŸ‘ 1 views

## Abstract Rat primary renal cortical tubular cells were exposed to seven test substances, some with, and some without, known direct renal tubular cell toxicity. Cells were exposed to the substances at either one‐third or one‐tenth of the TC~50~ for cytotoxicity for 6 h or 24 h, so as not to induc