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In UteroExposure to Low Doses of 2,3,7,8-Tetrachlorodibenzo-p-dioxin Alters Reproductive Development of Female Long Evans Hooded Rat Offspring

✍ Scribed by L.E. Gray Jr.; C. Wolf; Peter Mann; J.S. Ostby


Book ID
112266485
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
218 KB
Volume
146
Category
Article
ISSN
0041-008X

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## Abstract The cytochrome P450 (CYP) isoform CYP2C11 is specifically expressed in the liver of adult male rats, and 5α‐reductase is specifically expressed in the liver of the adult female rats. The sexually dimorphic expressions of these hepatic enzymes are regulated by the sex‐dependent profiles